Watch What Happens Live with Andy Cohen

Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.

Trending news, pop culture, social media, original videos and more come together in host Joel McHale's weekly comedy commentary show.

Late-night TV legend David Letterman hosts an intimate talk show featuring insightful conversations and fun-filled excursions with notable figures.

These half-hour specials showcased some of the best up-and-coming comedians of the moment. The show was a pivotal stepping stone for many of today's stand-up stars.

Each week, Jefferies tackles the week’s top stories from behind his desk and travels the globe to far-off locations to provide an eye opening look at hypocrisy around the world. Featuring interviews, international field pieces, and man on the ground investigations, Jim tackles the news of the day with no-bulls**t candor, piercing insight and a uniquely Aussie viewpoint.

Jerry takes his comedy pals out for coffee in a selection of his classic automobiles. Larry David sums it up best when he says, 'You've finally made a show about nothing.'

Comic Garry Shandling draws upon his own talk show experiences to create the character of Larry Sanders, a paranoid, insecure host of a late night talk show. Larry, along with his obsequious TV sidekick Hank Kingsley and his fiercely protective producer Artie, allows Garry Shandling and his talented writers to look behind the scenes and to show us a convincing slice of behind the camera life.

Building on their original talk show, comedian Norm Macdonald and sidekick Adam Eget sit down and chat with celebrity guests about their life, career and views in a somewhat unconventional and often irreverent way.

Host Chris Hardwick discusses episodes of the AMC television series The Walking Dead with guests, including celebrity fans, cast members, and crew from the series.

RuPaul's Drag Race season 7 queens Katya Zamolodchikova and Trixie Mattel in 'UNHhhh.' It's a show about nothing, and yet it's about everything.

A narrative series set in a limitless magical reality full of dynamic, hilarious characters and celebrity guests presenting sketches performed by a core cast of black women.

Tim and Eric Awesome Show, Great Job! is an American sketch comedy television series, created by and starring Tim Heidecker and Eric Wareheim, which premiered February 11, 2007 on Cartoon Network's Adult Swim comedy block and ran until May 2010. The program features surrealistic and often satirical humor, public-access television–style musical acts, bizarre faux-commercials, and editing and special effects chosen to make the show appear camp. The program featured a wide range of actors, spanning from stars such as Will Ferrell, John C. Reilly, David Cross, Bob Odenkirk, Will Forte and Zach Galifianakis, to alternative comedians like Neil Hamburger, to television actors like Alan Thicke, celebrity look-alikes and impressionists. The creators of the show have described it as "the nightmare version of television."