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Anna suffers from agoraphobia so crippling that when a trio of criminals break into her house, she cannot bring herself to flee. But what the intruders don't realize is that agoraphobia is not her only psychosis.

Unable to process the death of his daughter, Detective Boyd embarks on a hunt for a serial killer who murders according to a brutal tribal ritual: Muti. The only person who can help Boyd is Professor Mackles, an anthropologist who hides an unspeakable secret. The line between sanity and madness thins as Boyd goes deeper into the killer’s world.

After a young couple moves into a remote farmhouse with their infant son, the woman's struggles with postpartum psychosis begin to intensify... as the house reveals secrets of its own.

A troubled young woman becomes obsessed with her mysterious new neighbor, who bears a striking resemblance to the girl's dead mother.

Beautiful young manicurist Carole suffers from androphobia (the pathological fear of interaction with men). When her sister and roommate, Helen, leaves their London flat to go on an Italian holiday with her married boyfriend, Carole withdraws into her apartment. She begins to experience frightful hallucinations, her fear gradually mutating into madness.

A fashion designer suffers from a mysterious illness that puzzles her doctors and frustrates her husband until help arrives in the form of a Filipino caregiver who uses traditional folk healing to reveal a horrifying truth.

An African American male is imprisoned and placed in solitary confinement after being found guilty of murdering his wife, as he's haunted by internal demons and his dead wife, and pushed to the breaking point by an abusive female guard.

A single mom is raped by an invisible force. Her psychiatrist believes the experience stems from childhood trauma, while she knows something supernatural is at play.

A horror film told in three parts, from three perspectives, in which a mysterious transmission that turns people into killers invades every cell phone, radio, and television.

On a secluded family farm, a mother suffers a psychotic break due to postpartum depression, forcing the eldest son to protect his sibling from the mother they have always known and loved.

Neighbors in a block wake one morning to find they have been sealed inside their apartments. Can they work together to find out why? Or will they destroy each other in their fight to escape?

Grindhouse combines Robert Rodriguez's Planet Terror, a horror comedy about a group of survivors who battle zombie-like creatures, and Quentin Tarantino's Death Proof, an action thriller about a murderous stuntman who kills young women with modified vehicles. It is presented as a double feature with fictitious exploitation trailers preceding each segment.