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Milly and Louis, and their recently-widowed mom, Charlene, move to a new neighborhood. Once there, they all deal with a variety of personal problems, but Milly finds a friend in Eric, her autistic next door neighbor. Eric has a fascination with flight, and as the story progresses, he exerts an enthralling force of change on all those around him.

Stand-up comedian Max Bernal lives with his father Stan while struggling to co-parent his autistic son Ezra with his ex-wife. When forced to confront difficult decisions about their son's future, Max and Ezra embark on a cross-country road trip that has a transcendent impact on both their lives.

A recently widowed, now single father struggles to raise his sixth-grade son with autism. The pressure of his job and coping with the loss of his wife proves to push him nearly to the breaking point.

A teenage con artist tricks a desperate mother into hiring her as a live-in companion for her autistic daughter.

A love story between two savants with Asperger's syndrome, a kind of autism, whose conditions sabotage their budding relationship.

When Scott and Teresa LeRette learn that their son Austin is both autistic and has brittle bone disease, they initially worry for their son’s future. But with Scott’s growing faith and Austin’s incredible spirit, they become 'unbreakable', finding joy, gratitude, and courage even in the most trying times.

When Nick, who has Asperger's syndrome, struggles to carry on after the death of his brother Chaz, Chaz's best friend Randy takes Nick under his wing.

Corinne is a single mother of twin 5-year-old boys, Steven and Phillip, who are diagnosed with autism. Public school officials threaten to remove them from school due to their behavior, but through therapy, the boys are able to make major strides in their capabilities. A decade later, teens Steven and Phillip seek to prove they can handle high school while still struggling with their disorder.

Adam, a lonely man with Asperger's Syndrome, develops a relationship with his upstairs neighbor, Beth.

Marlo, a mother of three, including a newborn, is gifted a night nanny by her brother. Hesitant at first, she quickly forms a bond with the thoughtful, surprising, and sometimes challenging nanny named Tully.

A mentally ill young woman finds love with an eccentric man who models himself after Buster Keaton.

A massage therapist looking to overcome her addictions and reconnect with her son, whose father is an anthropologist in South America studying the Yanomani people, moves in with a wealthy ex-client in New Jersey.