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After he and his first wife separate, journalist David Sheff struggles to help their teenage son, who goes from experimenting with drugs to becoming devastatingly addicted to methamphetamine.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

An urgent phone call pulls a Yale Law student back to his Ohio hometown, where he reflects on three generations of family history and his own future.

A quiet, stoic man, lives a monk-like existence in self-imposed exile. When his estranged son is killed in a drug deal gone bad, he is left to look after a granddaughter he never knew existed, and he is forced back into a life he tried to put behind him.

This documentary follows three women — a fire chief, a judge, and a street missionary — as they battle West Virginia's devastating opioid epidemic.

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.

A college freshman returns to Los Angeles for Christmas at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.

A young drug-addled writer approaching the bottom of his descent submits to two months of agonizing detox at a treatment center in Minnesota.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

A chronicle of the crimes of Ted Bundy, from the perspective of his longtime girlfriend, Elizabeth Kloepfer, who refused to believe the truth about him for years.

Utah and his girlfriend Opal, are drug addicts living on the streets in rural Ohio. After getting recruited by body broker Wood and offered treatment in Los Angeles, Wood takes Utah under his wing and introduces him to treatment center mogul Vin. Wood and Vin bring Utah in on their lucrative and illegal dealings, where saving lives comes second to the bottom line.

A high school basketball player’s life turns upside down after free-falling into the harrowing world of drug addiction.