50/50

Famous and wealthy funnyman George Simmons doesn't give much thought to how he treats people until a doctor delivers stunning health news, forcing George to reevaluate his priorities with a little help from aspiring stand-up comic Ira.

An unlikely friendship between two neighbors becomes an unexpectedly emotional journey when the younger man is diagnosed with terminal cancer.

An unlikely friendship kindles between a struggling stand-up comedian from L.A. — forced to move back home to Eastern Long Island with his tail between his legs — and a tragically flawed, but charming and charismatic, alcoholic dermatologist. Discovering to be kindred spirits, each helps the other find healing, in addition to the confidence to face the "failures" in their lives.

A renowned professor is forced to reassess her life when she is diagnosed with terminal ovarian cancer.

When a group of old college friends reunite over a long weekend after one of them attempts suicide, old crushes and resentments shine light on their life decisions, and ultimately push friendships and relationships to the brink.

In the present, artist Tom Warshaw recalls his traumatic coming of age. As a 13-year-old growing up in New York City in 1973, Tom hangs out with Pappass, a mentally disabled man. With Tom's mother battling depression after the death of her husband, the young boy is left to his own devices. When Tom develops a crush on schoolmate Melissa, Pappass feels abandoned and begins behaving erratically.

Henry Poole abandons his fiancée and family business to spend what he believes are his remaining days alone. The discovery of a 'miracle' by a nosy neighbor ruptures his solitude and restores his faith in life.

Aspiring New York City artist John Hollar returns to his Middle America hometown on the eve of his mother’s brain surgery. Joined by his girlfriend Rebecca, eight months pregnant with their first child, John is forced to navigate the crazy world he left behind.

A man in his mid-20s, still living at home with his mother and stepfather, puts all his eggs in one basket: the girl who works at his local coffee shop. The problem is, she has a serious boyfriend. As they become closer, the line between friendship and intimacy is blurred, and the situation forces both to examine where they are in their lives.

A young filmmaker in 1960s Paris juggles directing a cheesy sci-fi debacle, directing his own personal art film, coping with his crumbling relationship with his girlfriend, and a new-found infatuation with the sci-fi film's starlet.

While caring for her brother along with her audacious mother, a teenager strikes up an unlikely friendship with an eccentric activist who is protesting one of the most landmark medical cases of all time.

The lives of several individuals intertwine as they go about their lives in their own unique ways, engaging in acts which society as a whole might find disturbing in a desperate search for human connection.