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Agnes and her two sisters struggle through a day in a home overrun by gamblers, thieves, and johns.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

After he and his first wife separate, journalist David Sheff struggles to help their teenage son, who goes from experimenting with drugs to becoming devastatingly addicted to methamphetamine.

When 13-year-old Tracy befriends Evie, the most popular girl in school, her life is turned upside down as Evie introduces her to a world of sex, drugs, and money. But it isn’t long before Tracy’s new lifestyle begins to take a heavy toll on her and her family.

A quiet, stoic man, lives a monk-like existence in self-imposed exile. When his estranged son is killed in a drug deal gone bad, he is left to look after a granddaughter he never knew existed, and he is forced back into a life he tried to put behind him.

The story of how George Jung, together with the Medellín Cartel led by Pablo Escobar, established the billion-dollar cocaine empire in the United States in the 1970s.

A recent widow invites her husband's troubled best friend to live with her and her two children. As he gradually turns his life around, he helps the family cope and confront their loss.

A logger defends his family from a group of dangerous drug runners.

In the late 1990s, up-and-coming mixed martial artist Mark Kerr aspires to become the greatest fighter in the world. However, he must also battle his opioid dependence and a volatile relationship with his girlfriend Dawn.

After their mother suffers a fatal overdose, two sisters fear being separated by the foster system and decide to hide her body. But when their lie risks being exposed, they must decide how far they’re willing to go to keep their secret.

In the streets of East Los Angeles, Manny is a formidable drug dealer. Impressed by his extravagant lifestyle and prowess, his young son, Kilo, yearns to follow in his footsteps. Kilo resolves to learn how to prosper in the drug world, and his new life as a dealer begins. In a world where a man wants everything, he may end up with nothing.