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The film contains five stories set on desolate stretches of a desert highway. Two men on the run from their past, a band on its way to a gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation are forced to confront their worst fears and darkest secrets in these interwoven tales.

When Cecilia's abusive ex takes his own life and leaves her his fortune, she suspects his death was a hoax. As a series of coincidences turn lethal, Cecilia works to prove that she is being hunted by someone nobody can see.

A boy named Harley and his family attend a taping of The Banana Splits TV show, which is supposed to be a fun-filled birthday for young Harley and business as usual for Rebecca, the producer of the series. But things take an unexpected turn - and the body count quickly rises. Can Harley, his mom and their new pals safely escape?

A woman wakes up injured in a basement surrounded by corpses. To survive, she pretends to be dead while a grotesque ritual unfolds in the house above.

With his partner Caprice, celebrity performance artist Saul Tenser publicly showcases the metamorphosis of his organs in avant-garde performances. An investigator from the National Organ Registry obsessively tracks their movements, which is when a mysterious group is revealed... Their mission — to use Tenser's notoriety to shed light on the next phase of human evolution.

Ebony Jackson, a struggling single mother fighting her personal demons, moves her family into a new home for a fresh start. But when strange occurrences inside the home raise the suspicions of Child Protective Services and threaten to tear the family apart, Ebony soon finds herself locked in a battle for her life and the souls of her children.

During its return to the earth, commercial spaceship Nostromo intercepts a distress signal from a distant planet. When a three-member team of the crew discovers a chamber containing thousands of eggs on the planet, a creature inside one of the eggs attacks an explorer. The entire crew is unaware of the impending nightmare set to descend upon them when the alien parasite planted inside its unfortunate host is birthed.

A grieving woman in a secluded forest encounters a killer who injects her with a paralytic drug. As her body shuts down, her fight for survival begins.

Gemma, a young mother raising her daughter in the house she grew up in, discovers she can travel into The Further, where she possesses an ability to bring what lives there back to the real world.

Nothing is what it seems when a twisted one-night stand spirals into a serial killer’s vicious murder spree.

When Eddie breaks into a luxury SUV, he steps into a deadly trap set by William, a self-proclaimed vigilante delivering his own brand of twisted justice. With no means of escape, Eddie must fight to survive in a ride where escape is an illusion, survival is a nightmare, and justice shifts into high gear.

Dr. Kelson finds himself in a shocking new relationship - with consequences that could change the world as they know it - and Spike's encounter with Jimmy Crystal becomes a nightmare he can't escape.